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List of substances for condition Group: Hematologic Disorder

All Human Animal Risk/Association ReviewRows: 359

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Curcumin 📋✍⛔38481552Curcumin in treatment of hematological cancers: Promises and challenges
Vitamin D3 📋✍⛔38715605The role of vitamin D in pediatric systemic lupus erythematosus - a double pawn in the immune and microbial balance
Vitamin C 📋✍⛔38454269Successful Treatment with Ascorbic Acid in a Case of Methemoglobinemia Due to Glucose-6-Phosphate Dehydrogenase Deficiency
Resveratrol 📋✍⛔38387900[Resveratrol Inhibits T-acute Lymphoblastic Leukemia in Mice by Regulating Notch1 Signaling Pathway]
Ginsenosides 📋✍⛔3870763820(S)-ginsenoside Rh2 ameliorates ATRA resistance in APL by modulating lactylation-driven METTL3
Quercetin 📋✍⛔38312709Effects of quercetin and extracts from Phyllanthus emblica, Morus alba, and Ginkgo biloba on platelet recovery in a rat model of chemotherapy-induced thrombocytopenia
EGCG 📋✍⛔37960113Antitumor Effect of Epigallocatechin Gallate and Vincristine in Mice with L5178Y Lymphoma
Ginseng 📋✍⛔37385213Homotherapy for heteropathy of Alzheimer's disease and anemia through reducing the expression of toll-like receptor and TNF by steamed Panax notoginseng
Berberine 📋✍⛔38518650Berberine promotes the degradation of phenylacetic acid to prevent thrombosis by modulating gut microbiota
Cannabidiol 📋✍⛔38268604A label free chemoproteomic-based platform to disclose cannabidiol molecular mechanism of action on chronic myelogenous leukemia cancer cells
Vitamin E 📋✍⛔37989321In vivo ameliorative effects of vitamin E against hydralazine-induced lupus
Melatonin 📋✍⛔37763082Cytotoxic Activity of Melatonin Alone and in Combination with Doxorubicin and/or Dexamethasone on Diffuse Large B-Cell Lymphoma Cells in In Vitro Conditions
Nattokinase 📋✍⛔37971898Study on the transport and internalization mechanism of dietary supplement nattokinase in the small intestine using animal and Caco-2 cell monolayer models
Pterostilbene 📋✍⛔35027628Pterostilbene downregulates BCR/ABL and induces apoptosis of T315I-mutated BCR/ABL-positive leukemic cells
Docosahexaenoic Acid 📋✍⛔38477125Crystalline silica-induced pulmonary inflammation and autoimmunity in mature adult NZBW/f1 mice: age-related sensitivity and impact of omega-3 fatty acid intervention
Metformin 📋✍⛔38286894Research Progress on the Use of Metformin in Leukemia Treatment
Omega-3 Fatty Acids 📋✍⛔38409715DHA and EPA in Sickle Cell Disease Favor Clinical Improvement and Contribute to Better Quality of Life: A Qualitative Systematic Review
Sulforaphane 📋✍⛔35182064The Inhibitory Effect of Sulforaphane on The Proliferation of Acute Myeloid Leukemia Cell Lines through Controlling miR-181a
Wogonin 📋✍⛔38698063On the mechanism of wogonin against acute monocytic leukemia using network pharmacology and experimental validation
Andrographolide 📋 38357243Andrographolide acts with dexamethasone to inhibit the growth of acute lymphoblastic leukemia CEM‑C1 cells via the regulation of the autophagy‑dependent PI3K/AKT/mTOR signaling pathway
Fucoidan 📋✍⛔37979755Orally administrated fucoidan and its low-molecular-weight derivatives are absorbed differentially to alleviate coagulation and thrombosis
N-Acetyl Cysteine 📋✍⛔38126172N-Acetyl Cysteine Prevents Arterial Thrombosis in a Dose-Dependent Manner In Vitro and in Mice
Papaya 📋✍⛔36119216Effect of doxycycline and doxycycline with carica papaya on thrombocytopenia and leucopenia in acute dengue fever patients
Retinoic Acid 📋 38204257Combination of Ethacrynic Acid and ATRA Triggers Differentiation and/or Apoptosis of Acute Myeloid Leukemia Cells through ROS
Angelica 📋✍⛔34690769Chinese Herbal Medicine Therapy Reduces the Risks of Overall and Anemia-Related Mortalities in Patients With Aplastic Anemia: A Nationwide Retrospective Study in Taiwan
Fisetin 📋✍⛔34804003Accumulation of Senescent Neural Cells in Murine Lupus With Depression-Like Behavior
Silymarin 📋✍⛔38283627Effect of oral silymarin on liver function in pediatric acute lymphoblastic leukemia in the maintenance phase: a double-blind randomized clinical trial
Thymoquinone 📋 ⛔37375831Thymoquinone Enhances Apoptosis of K562 Chronic Myeloid Leukemia Cells through Hypomethylation of SHP-1 and Inhibition of JAK/STAT Signaling Pathway
Fish Oil 📋✍⛔37892532Low-Dose Dietary Fish Oil Improves RBC Deformability without Improving Post-Transfusion Recovery in Mice
Green Tea Polyphenols 📋✍⛔38328786A randomized placebo-controlled clinical trial of oral green tea epigallocatechin 3-gallate on erythropoiesis and oxidative stress in transfusion-dependent β-thalassemia patients
L-Arginine 📋✍⛔37484717The Effect of L-Arginine Oral Supplementation on the Improvement of Cardiovascular Function and Pulmonary Artery Pressure in Patients with Major and Intermedia β-Thalassemia
Luteolin 📋✍⛔38150934Discovery and characterization of natural product luteolin as an effective inhibitor of human pyridoxal kinase
Reishi Mushrooms 📋✍⛔37833299Ganoderma lucidum methanolic extract as a potent phytoconstituent: characterization, in-vitro antimicrobial and cytotoxic activity
Apigenin 📋✍⛔36753951The anti-leukemic activity of a luteolin-apigenin enriched fraction from an edible and ethnomedicinal plant, Elsholtzia stachyodes, is exerted through an ER stress/autophagy/cell cycle arrest/ apoptotic cell death signaling axis
Aspirin 📋 ⛔37294478The efficacy of aspirin to inhibit platelet aggregation in patients hospitalised with a severe infection: a multicentre, open-label, randomised controlled trial
Dihydroartemisinin 📋 38669759Prednisone combined with Dihydroartemisinin attenuates systemic lupus erythematosus by regulating M1/M2 balance through the MAPK signaling pathway
Gallic Acid 📋 ⛔38062274The Effects of Resveratrol, Gallic Acid, and Piperine on the Expression of miR-17, miR-92b, miR-181a, miR-222, BAX, BCL-2, MCL-1, WT1, c-Kit, and CEBPA in Human Acute Myeloid Leukemia Cells and Their Roles in Apoptosis
Ginkgo Biloba 📋✍⛔35276465Preparation of a new component group of Ginkgo biloba leaves and investigation of the antihypertensive effects in spontaneously hypertensive rats
Kaempferol 📋✍⛔37096500[Inhibitory Effect of Kaempferol on Proliferation of KG1a Cells and Its Mechanism]
L-Glutamine 📋✍⛔38401036A Population Pharmacokinetic Analysis of L-Glutamine Exposure in Patients with Sickle Cell Disease: Evaluation of Dose and Food Effects
Phytochemicals 📋 38566147Natural products as potential drug treatments for acute promyelocytic leukemia
Vitamin B12 📋✍⛔37399204Impact of vitamin B12 on the reproductive health of women with sickle cell disease: a narrative review
Artemisinin 📋 38104159Artesunate acts through cytochrome c to inhibit growth of pediatric AML cells
Anthocyanins 📋✍⛔35924786Calcicoptosis induced by purple sweet potato anthocyanins through the nonosmotic regulation of the NFAT5/S100A4-S100A9 pathway in acute lymphoblastic leukemia
Burdock 📋 ⛔35401796Saccharides from Arctium lappa L. root reduce platelet activation and thrombus formation in a laser injury thrombosis mouse model
Genistein 📋✍⛔36765488[The In Vivo Intervention and Relative Mechanism of Genistein on the Inflammation and Thrombophilia in Lymphoma-Bearing Mice]
Grape Seed extract 📋✍⛔37832335Grape seed extract in combination with deferasirox ameliorates iron overload, oxidative stress, inflammation, and liver dysfunction in beta thalassemia children
Naringenin 📋✍⛔38116560Co-treatment of Naringenin and Ketoprofen-RGD Suppresses Cell Proliferation via Calmodulin/PDE/cAMP/PKA Axis Pathway in Leukemia and Ovarian Cancer Cells
Pomegranate 📋 ⛔37886154Tumor regression efficacy of Punica granatum L leaf extract against K562 leukemia cancer cells
Zinc 📋✍⛔36432604Association of Zinc with Anemia
Arctigenin 📋 38660844[Reversal Effect of Arctigenin on the Drug Resistance in Leukemia K562/A02 Cells and Its Mechanism]
Baicalin 📋✍⛔38071049[Effect of Baicalin on Pyroptosis of Diffuse Large B-Cell Lymphoma Cell Lines DB and Its Mechanism]
Cinnamon 📋✍⛔37240821The Anti-Cancer Effect of Cinnamon Aqueous Extract: A Focus on Hematological Malignancies
Cocoa 📋✍⛔38533262New light on changes in the number and function of blood platelets stimulated by cocoa and its products
Evening Primrose Oil 📋✍⛔35791734Supplementation with omega-3 or omega-6 fatty acids attenuates platelet reactivity in postmenopausal women
Gingerol 📋✍ 33373329Anti-neutrophil properties of natural gingerols in models of lupus
Hesperetin 📋 38423637Azacitidine-Hesperetin Combination Induces S-phase Cell Cycle Arrest and Apoptosis in Human Leukemia Cells
Iron 📋✍⛔36231177Effectiveness of Dietary Intervention with Iron and Vitamin C Administered Separately in Improving Iron Status in Young Women
Moringa Oleifera 📋✍⛔34929809Biscuits containing Moringa oleifera leaves flour improve conditions of anemia in pregnant women
Nigella Sativa 📋✍⛔35450390Nigella sativa L. as immunomodulator and preventive effect on renal tissue damage of lupus mice induced by pristane
Piperine 📋✍⛔38299416Randomised Clinical Trial Study: The Combination of Vitamin D and Curcumin Piperine Attenuates Disease Activity and Pro-inflammatory Cytokines Levels Insystemic Lupus Erythematosus Patients
Rapamycin 📋✍ 38530586Rapamycin increases leukemia cell sensitivity to chemotherapy by regulating mTORC1 pathway-mediated apoptosis and autophagy
Allicin 📋✍⛔35022635The garlic-derived organosulfur compound diallyl trisulphide suppresses tissue factor function
Ashwagandha 📋✍⛔35204712Computational Identification of BCR-ABL Oncogenic Signaling as a Candidate Target of Withaferin A and Withanone
Baicalein 📋✍⛔36869331Induction of DNMT1-dependent demethylation of SHP-1 by the natural flavonoid compound Baicalein overcame Imatinib-resistance in CML CD34+ cells
Bee Venom 📋✍⛔35205267Sweet Bee Venom Triggers Multiple Cell Death Pathways or Spurs Acute Cell Rupture According to Its Concentration in THP-1 Monocytic Leukemia Cells
DHEA 📋✍⛔37941864Dehydroepiandrosterone (DHEA) Supplementation in Rheumatic Diseases: A Systematic Review
Eicosapentaenoic Acid 📋✍⛔34211460Dietary Supplementation With Eicosapentaenoic Acid Inhibits Plasma Cell Differentiation and Attenuates Lupus Autoimmunity
Ellagic Acid 📋✍⛔37325443Ellagic Acid Exerts Dual Action to Curb the Pathophysiological Manifestations of Sickle Cell Disease and Attenuate the Hydroxyurea-Induced Myelosuppression in Berkeley Mice
Emodin 📋 ⛔35884943Emodin Ameliorates the Efficacy of Carfilzomib in Multiple Myeloma Cells via Apoptosis and Autophagy
Mulberry 📋 ⛔34584036The Root Bark of Morus alba L. and Its Bioactive Ingredient, Ursolic Acid, Suppress the Proliferation of Multiple Myeloma Cells by Inhibiting the Wnt/β-catenin Pathway
Myricetin 📋 ⛔37767484Myricetin as a promising inhibitor of platelet fibrinogen receptor in humans
Parthenolide 📋 37298119Parthenolide Induces ROS-Mediated Apoptosis in Lymphoid Malignancies
Puerarin 📋✍⛔33141989Puerarin sensitized K562/ADR cells by inhibiting NF-κB pathway and inducing autophagy
Raspberry 📋✍⛔38205364Effects of Black Raspberry Supplementation on Methylation Pathways in Vav-creAsxl1fl/flTet2fl/fl Double Knockout Mice with Early-stage Myelodysplastic Syndrome
Red Sage 📋✍⛔38423217Elucidating the distinctive regulatory effects and mechanisms of active compounds in Salvia miltiorrhiza Bunge via network pharmacology: Unveiling their roles in the modulation of platelet activation and thrombus formation
Salidroside 📋 37439434Salidroside affects the Th17/Treg cell balance in aplastic anemia via the STAT3/HIF-1α/RORγt pathway
Selenium 📋✍⛔35887320Therapeutic Benefits of Selenium in Hematological Malignancies
Tanshinone 📋 38706059[Study on the inhibitory and pro-apoptotic effects of different concentrations of total tanshinone alone and in combination with tyrosine kinase inhibitors on human myeloid leukemia cell lines]
Tomato 📋 ⛔36118749Water-soluble tomato concentrate modulates shear-induced platelet aggregation and blood flow in vitro and in vivo
Vitamin A 📋✍⛔24649891Effect of a single high dose vitamin A supplementation on the hemoglobin status of children aged 6-59 months: propensity score matched retrospective cohort study based on the data of Ethiopian Demographic and Health Survey 2011
Withaferin A 📋 35235278Withaferin A inhibits cell proliferation of U266B1 and IM-9 human myeloma cells by inducing intrinsic apoptosis
Aged Garlic 📋✍⛔27766480Aged garlic extract suppresses platelet aggregation by changing the functional property of platelets
Blueberry 📋✍⛔35631768Prediction of the Adult T-Cell Leukemia Inhibitory Activity of Blueberry Leaves/Stems Using Direct-Injection Electron Ionization-Mass Spectrometry Metabolomics
Caffeic Acid 📋✍⛔37800784Efficacy and safety of caffeic acid tablets in the treatment of thrombocytopenia: A systematic review and meta-analysis
Cat's Claw 📋✍⛔33091497Extracts from Uncaria tomentosa as antiplatelet agents and thrombin inhibitors - The in vitro and in silico study
Echinacea 📋✍⛔26626240Interactions Between Nutraceutical Supplements and Standard Acute Myeloid Leukemia Chemotherapeutics
Formononetin 📋 38528555Formononetin reverses Treg/Th17 imbalance in immune-mediated bone marrow failure mice by regulating the PI3K/Akt signaling pathway
Hesperidin 📋✍⛔36534417Evidence for Hesperidin as an Effective Factor in Initiating the Intrinsic Pathway of Apoptosis in KG1a Leukemia Cells
Honokiol 📋 38573223Honokiol induces apoptosis and autophagy in dexamethasone-resistant T-acute lymphoblastic leukemia CEM-C1 cells
Lipoic Acid 📋✍⛔33527721Effects of alpha lipoic acid on iron overload, lipid profile and oxidative stress indices in β-thalassemia major patients: A cross-over randomized controlled clinical trial
Mangiferin 📋 ⛔37356942[Experimental Study on the Mechanism of Mangiferin Inhibiting Malignant Biological Characteristics of Multiple Myeloma and Exerting Anticancer Effect]
Peony 📋 ⛔36569311Efficacy and safety of total glucosides of paeony in the treatment of systemic lupus erythematosus: A systematic review and meta-analysis
Roselle 📋✍⛔34771006Anti-Multiple Myeloma Potential of Secondary Metabolites from Hibiscus sabdariffa-Part 2
Rutin 📋✍⛔34888222Modulatory Effect of Rutin on the Antitumor Activity and Genotoxicity of Cisplatin in Tumor-Bearing Mice
Sea Buckthorn 📋✍⛔33761611Multidirectional effects of saponin fraction isolated from the leaves of sea buckthorn Elaeagnus rhamnoides (L.) A. Nelson
Vitamin K2 📋✍⛔26046133Vitamin K2 and Cotylenin A Synergistically Induce Monocytic Differentiation and Growth Arrest Along With the Suppression of c-MYC Expression and Induction of Cyclin G2 Expression in Human Leukemia HL-60 Cells
Astaxanthin 📋✍⛔35441937Astaxanthin decreases the growth-inhibitory dose of cytarabine and inflammatory response in the acute lymphoblastic leukemia cell line NALM-6
Astragalus Root 📋✍⛔28951880Chinese Herbal Formula, Modified Danggui Buxue Tang, Attenuates Apoptosis of Hematopoietic Stem Cells in Immune-Mediated Aplastic Anemia Mouse Model
Bay Leaf 📋 ⛔22017546Antioxidant and antiproliferative activity of Laurus nobilis L. (Lauraceae) leaves and seeds essential oils against K562 human chronic myelogenous leukaemia cells
Capsaicin 📋✍⛔36051054Targeting TRPV1 activity via high-dose capsaicin in patients with sickle cell disease
Carnosic Acid 📋 30003745Carnosic acid regulates cell proliferation and invasion in chronic myeloid leukemia cancer cells via suppressing microRNA-708
Carrot 📋 ⛔27275246Beetroot-Carrot Juice Intake either Alone or in Combination with Antileukemic Drug 'Chlorambucil' As A Potential Treatment for Chronic Lymphocytic Leukemia
Copper 📋✍⛔32744704A pilot study on secondary anemia in "frailty" patients treated with Ferric Sodium EDTA in combination with vitamin C, folic acid, copper gluconate, zinc gluconate and selenomethionine: safety of treatment explored by HRV non-linear analysis as predictive factor of cardiovascular tolerability
CoQ10 📋✍⛔36293203Coenzyme Q10 Attenuates Human Platelet Aggregation Induced by SARS-CoV-2 Spike Protein via Reducing Oxidative Stress In Vitro
Diallyl Disulfide 📋 38148345Diallyl disulfide synergizes with melphalan to increase apoptosis and DNA damage through elevation of reactive oxygen species in multiple myeloma cells
Dioscin 📋 38466633Dioscin alleviates aplastic anemia through regulatory T cells promotion
Flavonoids 📋 ⛔36358997Synergistically Anti-Multiple Myeloma Effects: Flavonoid, Non-Flavonoid Polyphenols, and Bortezomib
Frankincense 📋✍⛔38155908Boswellia carterii oleoresin extracts induce caspase-mediated apoptosis and G1 cell cycle arrest in human leukaemia subtypes
Garlic 📋✍⛔36222178A systematic review of randomized controlled trials related to the effects of garlic supplementation on platelet aggregation
Ginger 📋✍⛔36234956Polyphenol-Rich Ginger ( Zingiber officinale) for Iron Deficiency Anaemia and Other Clinical Entities Associated with Altered Iron Metabolism
Green Tea 📋✍⛔37035310Genetically predicted green tea intake and the risk of arterial embolism and thrombosis
Hawthorn 📋✍⛔33329023The Joint Effect of a Combination of Components From the Fruit of Crataegus pinnatifida Bge. Var. major N.E. Br. and the Root of Salvia miltiorrhiza Bge. With Exercises on Swimming in Focal Cerebral Infraction in Rat
L-Carnitine 📋✍⛔35293664Artemisinin and l-carnitine combination therapy alters the erythrocytes redox status
Nobiletin 📋✍ 32260160Nobiletin Promotes Megakaryocytic Differentiation through the MAPK/ERK-Dependent EGR1 Expression and Exerts Anti-Leukemic Effects in Human Chronic Myeloid Leukemia (CML) K562 Cells
Oleic Acid 📋 ⛔37817162The mechanism of oleic acid inhibiting platelet activation stimulated by collagen
Ollive Leaf extract 📋✍⛔37836379Hematinic Potential of Olive Leaf Extract: Evidence from an In Vivo Study in Mice and a Pilot Study in Healthy Human Volunteers
Pine Bark 📋✍⛔32429631Supplementary Management With Pycnogenol® in Patients With Lupus Vasculitis in Remission Phases: A Pilot, Concept Registry Study
Polyphenols 📋 36386899Polyphenols: Chemoprevention and therapeutic potentials in hematological malignancies
Procyanidins 📋 ⛔37246327Mechanism of procyanidin b2 in the treatment of chronic myeloid leukemia based on integrating network pharmacology and molecular docking
Rosemary 📋✍⛔29263624A Standardized Composition Comprised of Extracts from Rosmarinus officinalis, Annona squamosa and Zanthoxylum clava-herculis for Cellulite
Salvianolic Acid 📋 33847919Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway
Shogaol 📋 34930049Is 6-Shogaol an Effective Phytochemical for Patients With Lower-risk Myelodysplastic Syndrome? A Narrative Review
Silibinin 📋✍ 35093875The Natural Estrogen Receptor Beta Agonist Silibinin as a Promising Therapeutic Tool in Diffuse Large B-cell Lymphoma
Vitamin B6 📋✍⛔32860849Pyridoxine induces monocyte-macrophages death as specific treatment of acute myeloid leukemia
Vitamin B9 📋✍⛔36385742Impact of folic acid on regulatory B lymphocytes from patients with systemic lupus erythematosus in vitro
Vitamin K 📋✍⛔38201971Vitamin D and K Supplementation Is Associated with Changes in the Methylation Profile of U266-Multiple Myeloma Cells, Influencing the Proliferative Potential and Resistance to Bortezomib
Withanolides 📋 35204712Computational Identification of BCR-ABL Oncogenic Signaling as a Candidate Target of Withaferin A and Withanone
Alpha-Linolenic Acid 📋✍⛔37123064Perilla oil and α-linolenic acid ameliorated thrombosis in rats induced by collagen and epinephrine
Ashitaba 📋✍⛔37862040Supplementation with Ashitaba ( Angelica keiskei) Yellow Stem Exudate Prevents Aging-Induced Thrombotic Tendencies and Systemic Inflammation Without Affecting Body Weight Gain in Mice
Avocado 📋✍⛔26077472Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death
Barberry 📋✍⛔31001352In Vitro Antiatherothrombotic Effects of Extracts from Berberis Vulgaris L., Teucrium Polium L., and Orthosiphon Stamineus Benth
Betulinic Acid 📋 34573088Betulinic Acid-Doxorubicin-Drug Combination Induced Apoptotic Death via ROS Stimulation in a Relapsed AML MOLM-13 Cell Model
Bromelain 📋✍⛔35684129New Mechanisms of Bromelain in Alleviating Non-Alcoholic Fatty Liver Disease-Induced Deregulation of Blood Coagulation
Chokeberry 📋✍⛔22810463The polyphenol-rich extracts from black chokeberry and grape seeds impair changes in the platelet adhesion and aggregation induced by a model of hyperhomocysteinemia
Cordycepin 📋 37634411Pharmacological and therapeutic potentials of cordycepin in hematological malignancies
Cyanidin 📋✍ 27444805Anthocyanins From Roselle Extract Arrest Cell Cycle G2/M Phase Transition via ATM/Chk Pathway in p53-deficient Leukemia HL-60 Cells
Dihydromyricetin 📋✍⛔33924032Ampelopsin Inhibits Cell Proliferation and Induces Apoptosis in HL60 and K562 Leukemia Cells by Downregulating AKT and NF-κB Signaling Pathways
Escin 📋✍⛔21452372Escin sodium induces apoptosis of human acute leukemia Jurkat T cells
Ginkgetin 📋 38334198Ginkgetin effectively mitigates collagen and AA-induced platelet activation via PLCγ2 but not cyclic nucleotide-dependent pathway in human
Holy Basil 📋✍⛔37110523Inhibitory Potential of the Ocimum sanctum Phytochemicals on Bruton's Tyrosine Kinase, a Well-Known Drug Target for Treatment of Chronic Lymphocytic Leukemia: An In Silico Investigation
Horny Goat Weed 📋✍⛔34627438[Effect and Mechanism of Epimedium Polysaccharide on Bone Marrow Hematopoietic Function and Th17/Treg Balance in Aplastic Anemia]
Icariin 📋✍ 35708859Icariin protects bone marrow mesenchymal stem cells in aplastic anemia by targeting MAPK pathway
Icaritin 📋 38344310N-Ethyl-N-Nitrosourea Induced Leukaemia in a Mouse Model: Protective Effect of Icaritin via Inhibition of IL-6/JAK2/STAT3 Pathway Causes Apoptosis
Indian Gooseberry 📋 ⛔34850958Corilagin induces apoptosis and inhibits autophagy of HL‑60 cells by regulating miR‑451/HMGB1 axis
Lavender Essential Oil 📋✍⛔31991893Apoptotic Effects on HL60 Human Leukaemia Cells Induced by Lavandin Essential Oil Treatment
Lotus 📋 ⛔31969286Assessment of anti-coagulant activity of Nelumbo nucifera fruit
Medicinal Plants 📋 38566147Natural products as potential drug treatments for acute promyelocytic leukemia
Orange 📋 ⛔26434864Chemopreventive Actions of Blond and Red-Fleshed Sweet Orange Juice on the Loucy Leukemia Cell Line
Peanut 📋 ⛔21067217Arachidin-1, a peanut stilbenoid, induces programmed cell death in human leukemia HL-60 cells
Pomegranate Peel extract 📋✍⛔33133551Characterization of pomegranate peel extracts obtained using different solvents and their effects on cell cycle and apoptosis in leukemia cells
Quercitrin 📋 35456270Isolation and Characterisation of Quercitrin as a Potent Anti-Sickle Cell Anaemia Agent from Alchornea cordifolia
Rehmannia 📋✍⛔37556607Rehmannia Glutinosa Polysaccharide Regulates Bone Marrow Microenvironment via HIF-1α/NF-κB Signaling Pathway in Aplastic Anemia Mice
Rosmarinic Acid 📋✍ 37110523Inhibitory Potential of the Ocimum sanctum Phytochemicals on Bruton's Tyrosine Kinase, a Well-Known Drug Target for Treatment of Chronic Lymphocytic Leukemia: An In Silico Investigation
Sage 📋✍⛔30228801The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation
Sesamin 📋✍ 36397810Sesamin Acts as Anti-leukemic Compound Interacting with Novel Phosphoprotein Targets and Inducing Apoptosis in Leukemic Cells
Shiitake Mushrooms 📋✍⛔37396940Lentinan and β-glucan extract from shiitake mushroom, Lentinula edodes, alleviate acute LPS-induced hematological changes in mice
St. Johns Wort 📋✍⛔36141386Hypericum perforatum and Its Potential Antiplatelet Effect
Stinging Nettle 📋✍⛔33675488The Agglutinin of Common Nettle (Urtica dioica L.) Plant Effects on Gene Expression Related to Apoptosis of Human Acute Myeloid Leukemia Cell Line
Strawberry 📋✍⛔30771057Alkali-soluble pectin suppresses IgE production in human myeloma cell line in vitro
Sweet Potato 📋 ⛔35924786Calcicoptosis induced by purple sweet potato anthocyanins through the nonosmotic regulation of the NFAT5/S100A4-S100A9 pathway in acute lymphoblastic leukemia
Tannic Acid 📋✍⛔33128352Molecular docking-assisted screening reveals tannic acid as a natural protein disulphide isomerase inhibitor with antiplatelet and antithrombotic activities
Tetrahydrocurcumin 📋✍ 34428833Tetrahydrocurcumin Downregulates MAPKs/cPLA2 Signaling and Attenuates Platelet Thromboxane A2 Generation, Granule Secretion, and Thrombus Growth
Thyme 📋✍⛔33138135Induction of Apoptosis, Autophagy and Ferroptosis by Thymus vulgaris and Arctium lappa Extract in Leukemia and Multiple Myeloma Cell Lines
Trans-Resveratrol 📋 23161277Cytotoxic Effect of Natural Trans-Resveratrol Obtained From Elicited Vitis Vinifera Cell Cultures on Three Cancer Cell Lines
Vitamin B2 📋✍⛔36018769Riboflavin intake and status and relationship to anemia
Acacetin 📋 27779444Selective Anticancer Activity of Acacetin Against Chronic Lymphocytic Leukemia Using Both In Vivo and In Vitro Methods: Key Role of Oxidative Stress and Cancerous Mitochondria
Aloe-Emodin 📋 21978786Aloe-emodin as antiproliferative and differentiating agent on human U937 monoblastic leukemia cells
Amygdalin 📋✍⛔31649801Apoptosis Induction of Armeniacae Semen Extractin Human Acute Leukemia (NALM-6 and KG-1) Cells
Andrographis 📋✍⛔30243726In vitro large scale production of megakaryocytes to functional platelets from human hematopoietic stem cells
Apple 📋 ⛔33673327Beneficial Anti-Platelet and Anti-Inflammatory Properties of Irish Apple Juice and Cider Bioactives
Apple Vinegar 📋✍⛔35207526Anti-Anemic Effect of Antioxidant-Rich Apple Vinegar against Phenylhydrazine-Induced Hemolytic Anemia in Rats
Argan Oil 📋✍⛔23870174Argan oil prevents prothrombotic complications by lowering lipid levels and platelet aggregation, enhancing oxidative status in dyslipidemic patients from the area of Rabat (Morocco)
Asiatic Acid 📋 25815462Apoptosis of HL-60 human leukemia cells induced by Asiatic acid through modulation of B-cell lymphoma 2 family proteins and the mitogen-activated protein kinase signaling pathway
Balloon Flower 📋✍⛔37541375Platycodin D induces apoptotic cell death through PI3K/AKT and MAPK/ERK pathways and synergizes with venetoclax in acute myeloid leukemia
Bee Propolis 📋✍⛔29129989Inhibitory Effect of Propolis on Platelet Aggregation In Vitro
Beta-Carotene 📋✍⛔33413604In vitro anti-proliferative activity of selected nutraceutical compounds in human cancer cell lines
Beta-Sitosterol 📋✍⛔23640957Reactive oxygen species-mediated activation of AMP-activated protein kinase and c-Jun N-terminal kinase plays a critical role in beta-sitosterol-induced apoptosis in multiple myeloma U266 cells
Bilberry 📋✍⛔25757575Bilberry extract (Antho 50) selectively induces redox-sensitive caspase 3-related apoptosis in chronic lymphocytic leukemia cells by targeting the Bcl-2/Bad pathway
Black Pepper 📋✍⛔33884168Black pepper and piperine induce anticancer effects on leukemia cell line
Boswellic Acid 📋✍⛔27904529Anti-aggregatory effect of boswellic acid in high-fat fed rats: involvement of redox and inflammatory cascades
Camellia 📋 ⛔35592273Phytochemical constituents of Camellia osmantha fruit cores with antithrombotic activity
Carotenoids 📋✍⛔35565917Therapeutic Role of Carotenoids in Blood Cancer: Mechanistic Insights and Therapeutic Potential
Carvacrol 📋✍⛔35395969[Effect of Carvacrol on the Biological Behavior of Leukemia Cells and Its Mechanism]
Catechins 📋 34308509Green tea catechins in combination with irinotecan attenuates tumorigenesis and treatment-associated toxicity in an inflammation-associated colon cancer mice model
Chlorogenic Acid 📋✍⛔36355499Chlorogenic Acid Relieves the Lupus Erythematosus-like Skin Lesions and Arthritis in MRL/lpr Mice
Coconut 📋 ⛔38696690Ameliorative Effects of Coconut Water on Hematological and Lipid Profiles of Phenylhydrazine-treated Rats
Cordyceps 📋✍⛔37970560Antithrombotic and Antiplatelet Effects of Cordyceps militaris
Cranberry 📋✍⛔32143616Cranberry extract initiates intrinsic apoptosis in HL-60 cells by increasing BAD activity through inhibition of AKT phosphorylation
Crocin 📋✍⛔34276918Crocin Promotes Apoptosis in Human EBV-Transformed B-Lymphocyte via Intrinsic Pathway
Daidzein 📋✍⛔37569361Daidzein Inhibits Human Platelet Activation by Downregulating Thromboxane A2 Production and Granule Release, Regardless of COX-1 Activity
Dandelion 📋✍⛔30662779The Use of Natural Health Products Especially Papaya Leaf Extract and Dandelion Root Extract in Previously Untreated Chronic Myelomonocytic Leukemia
Date 📋 ⛔34929829Date palm (Phoenix dactylifera) consumption as a nutrition source for mild anemia
Delphinidin 📋 27444805Anthocyanins From Roselle Extract Arrest Cell Cycle G2/M Phase Transition via ATM/Chk Pathway in p53-deficient Leukemia HL-60 Cells
Diallyl Trisulfide 📋 33109572Potentiation of Differentiation and Apoptosis in a Human Promyelocytic Leukemia Cell Line by Garlic Essential Oil and Its Organosulfur Compounds
DIM 📋✍⛔35151647Diindolylmethane ameliorates platelet aggregation and thrombosis: In silico, in vitro, and in vivo studies
Diosmetin 📋 35164411Flavonoids: Antiplatelet Effect as Inhibitors of COX-1
Diosmin 📋✍⛔34229245Binding and antiplatelet activity of quercetin, rutin, diosmetin, and diosmin flavonoids
Eucalyptus 📋✍⛔346855971,8-Cineole Affects Agonists-Induced Platelet Activation, Thrombus Formation and Haemostasis
Eugenol 📋 38396774Eugenol Suppresses Platelet Activation and Mitigates Pulmonary Thromboembolism in Humans and Murine Models
Folate 📋✍⛔28588742Folate deficiency as predisposing factor for childhood leukaemia: a review of the literature
Food 📋 34007348Managing Genetic Hemochromatosis: An Overview of Dietary Measures, Which May Reduce Intestinal Iron Absorption in Persons With Iron Overload
Ginkgolides 📋 25223809Ginkgolide B inhibits platelet release by blocking Syk and p38 MAPK phosphorylation in thrombin-stimulated platelets
Glabridin 📋 36232674Glabridin, a Bioactive Flavonoid from Licorice, Effectively Inhibits Platelet Activation in Humans and Mice
Glycyrrhizic Acid 📋✍⛔22972479Glycyrrhizic acid induces apoptosis in WEHI-3 mouse leukemia cells through the caspase- and mitochondria-dependent pathways
Goat Milk 📋 ⛔37830350Fermented Goat's Milk Contributes to the Recovery of Iron Deficiency Anemia via Modulation of the Gut Microbiome
Guava 📋 ⛔33641960Anti-platelet activity and chemical characterization by UPLC-DAD-ESI-QTOF-MS of the main polyphenols in extracts from Psidium leaves and fruits
Hypericin 📋 35857290Efficacy and Safety of Topical Hypericin Photodynamic Therapy for Early-Stage Cutaneous T-Cell Lymphoma (Mycosis Fungoides): The FLASH Phase 3 Randomized Clinical Trial
Kiwifruit 📋✍⛔24219176Inhibitory effects of kiwifruit extract on human platelet aggregation and plasma angiotensin-converting enzyme activity
Licochalcones 📋 38350590Licochalcone A induces mitochondria-dependent apoptosis and interacts with venetoclax in acute myeloid leukemia
Linoleic Acid 📋✍⛔36076567Identification of linoleic acid as an antithrombotic component of Wenxin Keli via selective inhibition of p-selectin-mediated platelet activation
Loquat 📋✍⛔23429195Anti-Proliferative Activities and Apoptosis Induction by Triterpenes Derived from Eriobotrya japonica in Human Leukemia Cell Lines
Lycopene 📋✍⛔34799306Protective role of lycopene on blood haematology parameters in liver cirrhosis: Study in rats
Magnesium 📋✍⛔12774935Antithrombotic effects of magnesium sulfate in in vivo experiments
Maitake Mushrooms 📋 ⛔25351719Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study
Micronutrients 📋 ⛔37736537Therapeutic benefits of prophetic medicine remedies in treating hematological diseases (A review article)
Naringin 📋✍⛔37567521Naringin binds to protein disulfide isomerase to inhibit its activity and modulate the blood coagulation rates: Implications in controlling thrombosis
Nicotinamide 📋✍⛔37467318Nicotinamide enhances natural killer cell function and yields remissions in patients with non-Hodgkin lymphoma
Nimbolide 📋 35199915Nimbolide retards T cell lymphoma progression by altering apoptosis, glucose metabolism, pH regulation, and ROS homeostasis
Paeoniflorin 📋 36467552Paeoniflorin Inhibits LPS-Induced Activation of Splenic CD4+ T Lymphocytes and Relieves Pathological Symptoms in MRL/lpr Mice by Suppressing IRAK1 Signaling
Piperlongumine 📋 36220508Piperlongumine overcomes imatinib resistance by inducing proteasome inhibition in chronic myelogenous leukemia cells
Polydatin 📋✍ 35894200[Effect of polydatin on the proliferation and apoptosis of THP-1 cells and the mechanism]
Prebiotics 📋✍⛔36774028The Effect of Prebiotics on Human Iron Absorption: A Review
Probiotics 📋✍⛔37877130Probiotics as a complementary treatment in systemic lupus erythematosus: A systematic review
Punicalagin 📋✍⛔34760363Punicalagin, a pomegranate compound, induces apoptosis and autophagy in acute leukemia
Schisandra 📋✍⛔28194217Schisandra chinensis and Morus alba Synergistically Inhibit In Vivo Thrombus Formation and Platelet Aggregation by Impairing the Glycoprotein VI Pathway
Scutellarin 📋 37096506[Effect of Scutellarin on Proliferation of Acute Myeloid Leukemia Cells and Its Related Mechanism]
Serrapeptase 📋✍⛔31482506Fibrinolytic Enzymes for Thrombolytic Therapy
Skullcap 📋✍⛔35397287Antifibrotic activities of Scutellariae Radix extracts and flavonoids: Comparative proteomics reveals distinct and shared mechanisms
Spirulina 📋✍⛔37739734The effects of spirulina supplementation on serum iron and ferritin, anemia parameters, and fecal occult blood in adults with ulcerative colitis: A randomized, double-blinded, placebo-controlled trial
Theaflavins 📋✍ 35815842Theaflavin: a natural candidate to restrain thrombosis
Tongkat Ali 📋✍⛔34641483Quassinoids from the Roots of Eurycoma longifolia and Their Anti-Proliferation Activities
Ursolic Acid 📋✍⛔38144346Ursolic acid induces apoptosis and pyroptosis in Reh cells by upregulating of the JNK signalling pathway based on network pharmacology and experimental validation
Vitexin 📋 37110523Inhibitory Potential of the Ocimum sanctum Phytochemicals on Bruton's Tyrosine Kinase, a Well-Known Drug Target for Treatment of Chronic Lymphocytic Leukemia: An In Silico Investigation
Wine 📋 ⛔25690419Association of polyphenols from oranges and apples with specific intestinal microorganisms in systemic lupus erythematosus patients
Wormwood 📋✍⛔31649803Methanolic Extract from Aerial Parts of Artemisia Annua L. Induces Cytotoxicity and Enhances Vincristine-Induced Anticancer Effect in Pre-B Acute Lymphoblastic Leukemia Cells
Acai Berry 📋✍⛔16478240Açai (Euterpe oleracea Mart.) polyphenolics in their glycoside and aglycone forms induce apoptosis of HL-60 leukemia cells
Aloe Vera 📋✍⛔11007077Induction of Apoptosis in Human Leukaemic Cell Lines K562, HL60 and U937 by Diethylhexylphthalate Isolated From Aloe Vera Linne
Aloesin 📋 19941474Antitumor Properties and Modulation of Antioxidant Enzymes' Activity by Aloe Vera Leaf Active Principles Isolated via Supercritical Carbon Dioxide Extraction
Aloin 📋 19941474Antitumor Properties and Modulation of Antioxidant Enzymes' Activity by Aloe Vera Leaf Active Principles Isolated via Supercritical Carbon Dioxide Extraction
Anethole 📋 17709257Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis
Arctiin 📋 30668440Arctiin is a pharmacological inhibitor of STAT3 phosphorylation at tyrosine 705 residue and potentiates bortezomib-induced apoptotic and anti-angiogenic effects in human multiple myeloma cells
Arjuna 📋✍⛔33731264Protective effect of Terminalia arjuna against alcohol induced oxidative damage of rat erythrocyte membranes
Asafoetida 📋✍⛔31698777Farnesiferol C Induces Apoptosis in Chronic Myelogenous Leukemia Cells as an Imatinib Sensitizer via Caspase Activation and HDAC (Histone Deacetylase) Inactivation
Asiaticoside 📋 30785126Antitumor Activity of Asiaticoside Against Multiple Myeloma Drug-Resistant Cancer Cells Is Mediated by Autophagy Induction, Activation of Effector Caspases, and Inhibition of Cell Migration, Invasion, and STAT-3 Signaling Pathway
Asparagus 📋 ⛔37229244Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study
Astragalosides 📋✍⛔21875462[Mechanism of apoptosis in human leukemia NB4 cells induced by total astragalosides]
Basil 📋✍⛔31604407Apoptosis of Leukemia Cells by Ocimum basilicum Fractions Following TNF alpha Induced Activation of JNK and Caspase 3
Beets 📋✍⛔34322802Protective effect of Beta vulgaris roots supplementation on anemic phenylhydrazine-intoxicated rats
Bergamot 📋✍⛔36297603The Anticancer Effect of a Flavonoid-Rich Extract of Bergamot Juice in THP-1 Cells Engages the SIRT2/AKT/p53 Pathway
Beta-Lapachone 📋 20438329Beta-lapachone (LAPA) decreases cell viability and telomerase activity in leukemia cells: suppression of telomerase activity by LAPA
Bitter Melon 📋✍⛔36238266Anti-leukemic principle(s) from Momordica charantia seeds induce differentiation of HL-60 cells through ERK/MAPK signalling pathway
Black Cohosh 📋✍⛔35210810Aqueous Extract of Cimicifuga dahurica Reprogramming Macrophage Polarization by Activating TLR4-NF-κB Signaling Pathway
Black Tea 📋✍⛔35320401The effect of a natural polyphenol supplement on iron absorption in adults with hereditary hemochromatosis
Blackcurrant 📋✍⛔35293002The antioxidant, anti-inflammatory, and antiplatelet effects of Ribes rubrum L. fruit extract in the diabetic rats
Boric Acid 📋✍⛔38015327Boric Acid Affects Cell Proliferation, Apoptosis, and Oxidative Stress in ALL Cells
Brazil Nut 📋 ⛔34156903Impact of Brazil Nut ( Bertholletia excelsa, H.B.K.) Supplementation on Body Composition, Blood Pressure, and the Vascular Reactivity of Wistar Rats When Submitted to a Hypersodium Diet
Cabbage 📋 ⛔35687076Cabbage juice supplementation abrogates Lead acetate-induced haematological and haemorheological imbalances in male Wistar rat
Caffeine 📋✍⛔32703116Caffeine intake influences disease activity and clinical phenotype in systemic lupus erythematosus patients
Capsanthin 📋 21620794Carotenoids Inhibit Proliferation and Regulate Expression of Peroxisome Proliferators-Activated Receptor Gamma (PPARγ) in K562 Cancer Cells
Cardamom 📋✍⛔25410063Exploration for the multi-effect of cardamom in's resistance to multiple myeloma
Cardamonin 📋 37749558Raptor mediates the selective inhibitory effect of cardamonin on RRAGC-mutant B cell lymphoma
Chamomile 📋✍⛔31921608Effect of chamomile on chemotherapy-induced neutropenia in pediatric leukemia patients: A randomized triple-blind placebo-controlled clinical trial
Chlorella 📋✍⛔10458539Effects of Chlorella vulgaris on bone marrow progenitor cells of mice infected with Listeria monocytogenes
Chrysin 📋✍⛔34151613Antisickling effect of chrysin is associated with modulation of oxygenated and deoxygenated haemglobin via alteration of functional chemistry and metabolic pathways of human sickle erythrocytes
Cinnamic Acid 📋 35585382Ethacrynic acid and cinnamic acid combination exhibits selective anticancer effects on K562 chronic myeloid leukemia cells
Citral 📋 14758720Induction of apoptosis by Citrus paradisi essential oil in human leukemic (HL-60) cells
Coffee 📋✍⛔33375091Anti-Platelet Aggregation and Anti-Cyclooxygenase Activities for a Range of Coffee Extracts ( Coffea arabica)
Colostrum 📋✍⛔37174290Utilization of Dairy By-Products as a Source of Functional and Health Compounds-The Role of Ovine Colostrum and Milk Whey on Chronic Myeloid Leukemia Cells
Coptis Chinensis 📋 ⛔28951880Chinese Herbal Formula, Modified Danggui Buxue Tang, Attenuates Apoptosis of Hematopoietic Stem Cells in Immune-Mediated Aplastic Anemia Mouse Model
Coriander 📋 ⛔34451867Antileukemic Activity and Molecular Docking Study of a Polyphenolic Extract from Coriander Seeds
Coumaric acid 📋 37096516[Effect of P-coumaric Acid on Apoptosis of Multiple Myeloma Cells Based on Oxidative Stress]
Creatine 📋✍⛔18421708Creatine Monohydrate Attenuates Body Fat Accumulation in Children With Acute Lymphoblastic Leukemia During Maintenance Chemotherapy
Crocetin 📋 30203596Study of the mechanisms of crocetin-induced differentiation and apoptosis in human acute promyelocytic leukemia cells
D-Mannose 📋✍⛔35001876Effect of D-mannose on Philadelphia chromosome-positive leukemia cells
Deodar Cedar 📋 35325515Attenuation of cisplatin induced myelosuppression by methanol extract of Cedrus deodara in wistar rats
Durian 📋 ⛔37242300Elucidation of the Anticancer Mechanism of Durian Fruit ( Durio zibethinus) Pulp Extract in Human Leukemia (HL-60) Cancer Cells
Eclipta Alba 📋✍ 34726823Environmental pollutant N-N'ethylnitrosourea-induced leukemic NLRP3 inflammasome activation and its amelioration by Eclipta prostrata and its active compound wedelolactone
Eurycomanone 📋 25230121Eurycomanone and eurycomanol from Eurycoma longifolia Jack as regulators of signaling pathways involved in proliferation, cell death and inflammation
Fennel Essential Oil 📋✍⛔17709257Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis
Fenugreek 📋✍⛔23110539Fenugreek Extract as an Inducer of Cellular Death via Autophagy in Human T Lymphoma Jurkat Cells
Ferulic Acid 📋✍⛔37846672[Inhibition of Ferulic Acid on U937 Cell Growth and Its Related Mechanism]
Feverfew 📋✍⛔34060380Leukemia Chemoprevention and Therapeutic Potentials: Selected Medicinal Plants with Anti-Leukemic Activities
Fish 📋 ⛔11176840Intake of fish and omega-3 fatty acids and risk of stroke in women
Gamma-Linolenic Acid 📋✍⛔11426562Gamma-linolenic acid induces apoptosis in B-chronic lymphocytic leukaemia cells in vitro
Gardenia 📋 ⛔32101773Discovery and identification of antithrombotic chemical markers in Gardenia Fructus by herbal metabolomics and zebrafish model
Geniposide 📋 33162801Geniposide inhibits proliferation and induces apoptosis of diffuse large B-cell lymphoma cells by inactivating the HCP5/miR-27b-3p/MET axis
Ginger extract 📋✍⛔31214760Ginger extract has anti-leukemia and anti-drug resistant effects on malignant cells
Ginkgolic Acid 📋 28208828Ginkgolic Acid C 17:1, Derived from Ginkgo biloba Leaves, Suppresses Constitutive and Inducible STAT3 Activation through Induction of PTEN and SHP-1 Tyrosine Phosphatase
Glucosamine 📋✍⛔37329549Glucosamine effects on platelet aggregation of type 2 diabetes mellitus patients: in vitro assays
Glutathione 📋✍⛔35016427Glutathione combined with mecobalamin in the treatment of chemotherapy-induced peripheral neuropathy in multiple myeloma: a retrospective clinical study
Glycyrrhetinic Acid 📋 24412029Discovery of glycyrrhetinic acid as an orally active, direct inhibitor of blood coagulation factor xa
Gotu Kola 📋✍⛔35675643Centella asiatica Modulates Nrf-2 Antioxidant Mechanisms and Enhances Reactive Oxygen Species-Mediated Apoptotic Cell Death in Leukemic (THP-1) Cells
Grape 📋 ⛔35320401The effect of a natural polyphenol supplement on iron absorption in adults with hereditary hemochromatosis
Grapefruit 📋 ⛔36248996The successful combination of grapefruit juice and venetoclax in an unfit acute myeloid leukemia patient with adverse risk: A case report
Grapefruit Essential Oil 📋✍⛔14758720Induction of apoptosis by Citrus paradisi essential oil in human leukemic (HL-60) cells
Grapefruit extract 📋✍⛔27465424Pure total flavonoids from Citrus paradisi Macfad induce leukemia cell apoptosis in vitro
Graviola 📋✍⛔25539720Antiproliferative activity and induction of apoptosis by Annona muricata (Annonaceae) extract on human cancer cells
Guggulsterone 📋 36428714Guggulsterone Induces Apoptosis in Multiple Myeloma Cells by Targeting High Mobility Group Box 1 via Janus Activated Kinase/Signal Transducer and Activator of Transcription Pathway
Honey 📋✍⛔37458648Comparative effectiveness of adding omega-3 and Manuka honey combination to conventional therapy in preventing and treating oxidative stress in pediatric β-thalassemia major - a randomized clinical trial
Hydroxytyrosol 📋 35806065Involvement of the PI3K/AKT Intracellular Signaling Pathway in the AntiCancer Activity of Hydroxytyrosol, a Polyphenol from Olea europaea, in Hematological Cells and Implication of HSP60 Levels in Its Anti-Inflammatory Activity
Isoflavones 📋✍⛔19394691GCP, a Genistein-Rich Compound, Inhibits Proliferation and Induces Apoptosis in Lymphoma Cell Lines
Isoliquiritigenin 📋 37082661The inhibitory effect of isoliquiritigenin on human platelets in vitro
Jasmine 📋 ⛔36861238Evaluation of Anti-clotting and thrombolytic potential of the aqueous-methanolic extract of Jasminum sambac
Kale 📋 37048295Anti-Leukemic Effects on a U937 Cell Line of Fresh and Steamed Chinese Kale Juice and Their Pro-Apoptotic Effects via a Caspase-Dependent Pathway
Krill Oil 📋✍⛔38139268Antarctic Krill Oil from Euphausia superba Ameliorates Carrageenan-Induced Thrombosis in a Mouse Model
Kudzu Root 📋✍⛔31878046Attenuation of STAT3 Signaling Cascade by Daidzin Can Enhance the Apoptotic Potential of Bortezomib against Multiple Myeloma
L-Tryptophan 📋✍⛔10834318Enhanced tryptophan degradation in systemic lupus erythematosus
Laminaria 📋✍⛔35566376Physicochemical Properties and Anticoagulant Activity of Purified Heteropolysaccharides from Laminaria japonica
Lemongrass 📋✍⛔29340014Cymbopogon citratus and Camellia sinensis extracts selectively induce apoptosis in cancer cells and reduce growth of lymphoma xenografts in vivo
Licorice Root 📋✍⛔28089715Ameliorating effects of herbal formula hemomine on experimental subacute hemorrhagic anemia in rats
Ligustilide 📋 38183698Dual role of Nrf2/HO-1 pathway in Z-ligustilide-induced ferroptosis against AML cells
Limonin 📋 33841805Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity
Linalool 📋 ⛔32934748Linalool inhibits the growth of human T cell acute lymphoblastic leukemia cells with involvement of the MAPK signaling pathway
Magnolol 📋 33440989Magnolol suppressed cell migration and invasion and induced cell apoptosis via inhibition of the NF-κB signaling pathway by upregulating microRNA-129 in multiple myeloma
Malvidin 📋 12502387Induction of apoptosis in cancer cells by Bilberry (Vaccinium myrtillus) and the anthocyanins
Mango 📋 ⛔31671743Antiplatelet Activity of Natural Bioactive Extracts from Mango ( Mangifera Indica L.) and its By-Products
Millet 📋 38419846Does millet consumption contribute to raising blood hemoglobin levels compared to regular refined staples?: a systematic review and meta-analysis
Minerals 📋 37567355Therapeutic effect of trace elements on multiple myeloma and mechanisms of cancer process
Modified Citrus Pectin 📋✍⛔21816083Activation of human T-helper/inducer cell, T-cytotoxic cell, B-cell, and natural killer (NK)-cells and induction of natural killer cell activity against K562 chronic myeloid leukemia cells with modified citrus pectin
Mugwort 📋 ⛔36382259Artemisia vulgaris inhibits BCR/ABL and promotes apoptosis in chronic myeloid leukemia cells
Myrrh 📋✍⛔32293402Frankincense and myrrh and their bioactive compounds ameliorate the multiple myeloma through regulation of metabolome profiling and JAK/STAT signaling pathway based on U266 cells
Myrtle 📋✍⛔36501085Antileukemic, Antioxidant, Anti-Inflammatory and Healing Activities Induced by a Polyphenol-Enriched Fraction Extracted from Leaves of Myrtus communis L
NAD 📋 33790300Type I interferons affect the metabolic fitness of CD8 + T cells from patients with systemic lupus erythematosus
Nicotinamide Riboside 📋✍⛔30849366The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance
Nitrate 📋✍⛔20089363Potential utility of full-spectrum antioxidant therapy, citrulline, and dietary nitrate in the management of sickle cell disease
NMN 📋✍⛔33790300Type I interferons affect the metabolic fitness of CD8 + T cells from patients with systemic lupus erythematosus
Nutmeg 📋✍⛔24792648Myristicin from nutmeg induces apoptosis via the mitochondrial pathway and down regulates genes of the DNA damage response pathways in human leukaemia K562 cells
Olive Oil 📋✍⛔26525667Dietary extra virgin olive oil attenuates kidney injury in pristane-induced SLE model via activation of HO-1/Nrf-2 antioxidant pathway and suppression of JAK/STAT, NF-κB and MAPK activation
Oregano 📋✍⛔27470342Cooperative antiproliferative and differentiation-enhancing activity of medicinal plant extracts in acute myeloid leukemia cells
Oyster 📋 ⛔37960326Oral Zinc-Rich Oyster Supplementation Corrects Anemia in Rats
Papain 📋✍⛔38069092Unveiling the Potent Fibrino(geno)lytic, Anticoagulant, and Antithrombotic Effects of Papain, a Cysteine Protease from Carica papaya Latex Using κ-Carrageenan Rat Tail Thrombosis Model
Parsley 📋 ⛔34012875Oral treatment with a chemically characterized parsley ( Petroselinum crispum var . neapolitanum Danert) aqueous extract reduces thrombi formation in rats
Patchouli 📋✍⛔34136185Pogostemon cablin extract as an anticancer agent on human acute myeloid leukemia
Peppermint 📋✍⛔36923503Anti-leukemic effect of menthol, a peppermint compound, on induction of apoptosis and autophagy
Perilla 📋✍ 37123064Perilla oil and α-linolenic acid ameliorated thrombosis in rats induced by collagen and epinephrine
Phytoestrogens 📋 ⛔33603542Induction of cell death and modulation of Annexin A1 by phytoestrogens in human leukemic cell lines
Polypodium Leucotomos 📋✍⛔22611747Subacute cutaneous lupus erythematosus: a case report of Polypodium leucotomos as an adjuvant therapy
Rhodiola 📋✍⛔35695011Rhodiola rosea polysaccharides promote the proliferation of bone marrow haematopoietic progenitor cells and stromal cells in mice with aplastic anaemia
Rosehip 📋✍⛔27470342Cooperative antiproliferative and differentiation-enhancing activity of medicinal plant extracts in acute myeloid leukemia cells
Saffron 📋✍⛔30644127The Antileukemic Effects of Saffron (Crocus Sativus L.) and Its Related Molecular Targets: A Mini Review
Saw Palmetto 📋✍⛔19578780Serenoa Repens Induces Growth Arrest and Apoptosis of Human Multiple Myeloma Cells via Inactivation of STAT 3 Signaling
Sea Cucumber 📋 30340002Primary structure and anticoagulant activity of fucoidan from the sea cucumber Holothuria polii
Soy Isoflavones 📋✍⛔18755863Soy Isoflavones Supplementation Alleviates Disease Severity in Autoimmune-Prone MRL-lpr/lpr Mice
Star Anise 📋✍⛔31915450Systemic Pharmacological Approach to Identification and Experimental Verification of the Effect of Anisi Stellati Fructus Extract on Chronic Myeloid Leukemia Cells
Stevia 📋✍⛔33832898Hematological and toxicological effects of aqueous leaf extract of Stevia rebaudiana Bertoni in normal rat modals
Tangeretin 📋 20077418The flavonoid tangeretin activates the unfolded protein response and synergizes with imatinib in the erythroleukemia cell line K562
Tea 📋 29340014Cymbopogon citratus and Camellia sinensis extracts selectively induce apoptosis in cancer cells and reduce growth of lymphoma xenografts in vivo
Theobromine 📋✍⛔25869509Effects of high flavanol dark chocolate on cardiovascular function and platelet aggregation
Thymol 📋✍⛔33466806New Anti-Leukemic Effect of Carvacrol and Thymol Combination through Synergistic Induction of Different Cell Death Pathways
TUDCA 📋✍⛔32104390Preparation and toxicity evaluation of a novel nattokinase-tauroursodeoxycholate complex
Urolithins 📋 34067305Urolithin A and B Alter Cellular Metabolism and Induce Metabolites Associated with Apoptosis in Leukemic Cells
Vitamin B1 📋✍⛔34193235Evaluation of thiamine as adjunctive therapy in COVID-19 critically ill patients: a two-center propensity score matched study
Vitamin K2 mk-7 📋✍ 36501221The Evidence That 25(OH)D3 and VK2 MK-7 Vitamins Influence the Proliferative Potential and Gene Expression Profiles of Multiple Myeloma Cells and the Development of Resistance to Bortezomib
Walnut 📋 ⛔28945497Antiproliferative Activity of Walnut (Juglans regia L.) Proteins and Walnut Protein Hydrolysates
Wasabi 📋 ⛔37047794Anti-Cancer Effects of Oxygen-Atom-Modified Derivatives of Wasabi Components on Human Leukemia Cells
Wenxin Keli 📋✍⛔36076567Identification of linoleic acid as an antithrombotic component of Wenxin Keli via selective inhibition of p-selectin-mediated platelet activation
Whey Protein 📋✍⛔37174290Utilization of Dairy By-Products as a Source of Functional and Health Compounds-The Role of Ovine Colostrum and Milk Whey on Chronic Myeloid Leukemia Cells
Wood Ear Mushrooms 📋 ⛔35467804Human Hemoglobin S Erythrocyte-Stabilizing and Antisickling Potential of Extract of Wood Ear Mushroom, Auricularia auricula (Agaricomycetes)